Pietruszka Group

Group leader

Title

Name

First Name

Position

Prof. Dr.

Pietruszka

Jörg

Head of Institute

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BioStruct Fellow

Title

Name

First Name

Position

Msc.

Classen

Thomas

PhD student

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Further Team Members

Technicians:

6

Master/Diploma students:

6

PHD/MD students:

16


Contact

Jörg Pietruszka
Institute of Bioorganic Chemistry
Forschungszentrum Jülich
Stetternicher Forst, Geb. 15.8
52426 Jülich

Tel : +49 2461 614158
Fax: +49 2461 616196

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Special Methodical Expertise

  • Applied Biocatalysis
  • Assay Development

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Main areas of research interest

  • Natural Product Synthesis
  • Organoboron Chemistry
  • Biocatalysis
  • Assay Development
  • Enantioselectivity Screening

Facilities

The laboratories cover the following gene technology security levels:

S1

 

Laboratory Equipment

General equipment available in the laboratories:

  • Biotechnology
  • Org. Chemistry


Special equipment, which is not generally available in most laboratories:

  • HTS-NMR
  • HTS-HPLC/CD


Non-standard methods, which are established in the laboratory:

  • Chemoenzymatic total synthesis of natural products
  • Utilizing stable boronic esters

Important References

  • Martina Bischop, Verena Doum, Anja C. M. Nordschild (née Rieche), Jörg Pietruszka, and Diana Sandkuhl,
    Synthesis 2010, 527-537;
    "Total Synthesis of Halicholactone and Neohalicholactone"
  • Jörg Pietruszka, Melanie Schölzel,
    Adv. Synth. Catal. 2012, 354, 751-756;
    "Ene Reductase-catalysed Synthesis of (R)-Profen Derivatives"
  • Irene Kullartz, Jörg Pietruszka,
    J. Biotechnol. 2012, doi:10.1016/j.biotec.2011.12.018;
    "Cloning and characterisation of a new 2-deoxy-D-ribose-5-phosphate aldolase from Rhodococcus erythropolis"
  • Natalie Hoffmann, Jörg Pietruszka, Christoph Söffing,
    Adv. Synth. Catal. 2012, 354, 959-963;
    "From Sophorose Lipids to Natural Product Synthesis"
  • Jörg Pietruszka, Chuan Wang,
    ChemCatChem 2012, 4, doi:10.1002/cctc.201200051;
    "Laccase-catalyzed 3-Arylation of 3-Substituted Oxindoles"
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